Gynefix vs Progestogen-only / Mini pill

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Gynefix

Add your Gynefix review

Progestogen-only / Mini pill

£From £0.22/day

Overview

Rated 4.4

12 reviews

5 years

Frequency

Over 99%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Rated 2.7

1398 reviews

Daily

Frequency

91% - 99+%

Effectiveness

None

Blood clot risk

None

Effect on fertility

Gynefix ingredients

The GyneFix is made of a non-biodegradable suture thread made of surgical 00 monofilament polypropylene (AKA a type of plastic) on which six copper tubes are threaded

Progestogen-only / Mini pill ingredients

Main hormones in Progestogen-only / Mini pill

progestogen

What Lowdown reviewers say

58% no impact on mood

33% regular periods

83% no impact

92% no impact

83% no impact on skin

Cycle return

Not enough data to say

31% somewhat negative

44% stopped periods

49% lost sex drive

44% no impact

46% no impact on skin

Cycle return

38% don’t know impact

Benefits: What this contraceptive can help with

There are no benefits that are recognised in scientific research or guidelines for this contraceptive

Period pain

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£From £0.22/day

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Real life reviews from people like you

Gynefix reviews

12 reviews

Gynefix  
Used for 12 - 18 mo
28 years old
🇬🇧 UK
  •  27th Apr 25

Gynefix  

Like many others, I found myself unable to decide between a coil (painful) and hormones (just dont want hormones). Gynefix has been the perfect in-between solution for me. Hormone-free, but also not painful. Insertion was a bit uncomfortable. The gyno needs to pierce your uterus wall. It felt a bit like getting a tiny push somewhere deep inside which, rather than super painful, was just a weird feeling which is what makes it uncomfortable. During the week after I could still feel that spot but again it wasn't really painful just weird to be aware of an internal organ like that. Other than having to avoid strenuous exercise for a few weeks, the recovery was very smooth and I had no issues. You cannot feel the gynefix inside you which is amazing. I have noticed no difference in my periods other than that 2 weeks before my period is due, I get some light spotting. I was afraid that during sex, the guy would feel the removal thread, but this was not the case. The thread also curls around the cervix a bit (over time) which makes it even less noticeable. Maintenance wise it's also great. Just visit the gyno every couple of months to get an ultrasound and make sure the Gynefix is still in place. You get 5 years of protection. I wish the gynefix was advertised to more people because I believe it is an awesome solution for anyone that is looking for a pain-free, hormone-free, hassle free contraceptive.

Read more

Top side effects not reported

0 helpful

0 comments

Gynefix  
Used for 1 - 3 mo
30 years old
🇬🇧 UK
  •  6th Mar 25

Gynefix  

I got my gynefix mini online and had it inserted at the John Hunter clinic in London. I had paraguard before which gave me terrible cramps and incredibly heavy periods: I had Jaydess for 3 years which gave low but manageable mood but I started having terrible back pains either it. Once I had it removed, back pains stopped. I didn’t use anything for a while and then tried the implant, which was awful! It gave me terrible mood swings and anger! Went back to jaydess and back pains returned and low mood. I started looking for other options and found gynefix and I am so glad I did! Insertion was painful and my periods are significantly heavier but nothing I can’t live with. No back-pains, no horrible craps and no mood effects! Thank you whoever created this! I really forget it is there and only sometimes can slightly feel it, but this is by far the best contraception I’ve tried! It was hard to find a dr to get it fitted and I had to order it myself as NHS don’t supply it, but worth it!


Very positive mood

0 helpful

1 comments

Gynefix  
Used for 12 - 18 mo
23 years old
🇬🇧 UK
  •  4th Jan 25

Gynefix  

Got one at mortimer market in 2023 and other than a slight increase in discharge (normal discharge), which to be honest I don't think is related to the gynefix, I have had an amazing experience with the gynefix, I just wish it lasted longer than 5 years! Insertion was very smooth; uncomfortable/painful for sure but nothing terrible and not the worst pain of my life, I was able to walk home after the procedure. Had spotting / light bleeding throughout my cycle for maybe a month or two, and I remember having spotting for a few months, but honestly nothing crazy or super annoying. My period was a bit heavier for a few months after insertion but now it is back to my normal (I had light, minimal pain periods before the gynefix for context!). I love it and wish it was more available in the UK, fear that when I need it out I wont be able to get it on the NHS and I can't see myself wanting any other contraception.


Very positive mood

0 helpful

0 comments

Gynefix  
Used for 12 - 18 mo
28 years old
🇬🇧 UK
  •  27th Apr 25

Gynefix  

Like many others, I found myself unable to decide between a coil (painful) and hormones (just dont want hormones). Gynefix has been the perfect in-between solution for me. Hormone-free, but also not painful. Insertion was a bit uncomfortable. The gyno needs to pierce your uterus wall. It felt a bit like getting a tiny push somewhere deep inside which, rather than super painful, was just a weird feeling which is what makes it uncomfortable. During the week after I could still feel that spot but again it wasn't really painful just weird to be aware of an internal organ like that. Other than having to avoid strenuous exercise for a few weeks, the recovery was very smooth and I had no issues. You cannot feel the gynefix inside you which is amazing. I have noticed no difference in my periods other than that 2 weeks before my period is due, I get some light spotting. I was afraid that during sex, the guy would feel the removal thread, but this was not the case. The thread also curls around the cervix a bit (over time) which makes it even less noticeable. Maintenance wise it's also great. Just visit the gyno every couple of months to get an ultrasound and make sure the Gynefix is still in place. You get 5 years of protection. I wish the gynefix was advertised to more people because I believe it is an awesome solution for anyone that is looking for a pain-free, hormone-free, hassle free contraceptive.


Top side effects not reported

0 helpful

0 comments

Gynefix  
Used for 1 - 3 mo
30 years old
🇬🇧 UK
  •  6th Mar 25

Gynefix  

I got my gynefix mini online and had it inserted at the John Hunter clinic in London. I had paraguard before which gave me terrible cramps and incredibly heavy periods: I had Jaydess for 3 years which gave low but manageable mood but I started having terrible back pains either it. Once I had it removed, back pains stopped. I didn’t use anything for a while and then tried the implant, which was awful! It gave me terrible mood swings and anger! Went back to jaydess and back pains returned and low mood. I started looking for other options and found gynefix and I am so glad I did! Insertion was painful and my periods are significantly heavier but nothing I can’t live with. No back-pains, no horrible craps and no mood effects! Thank you whoever created this! I really forget it is there and only sometimes can slightly feel it, but this is by far the best contraception I’ve tried! It was hard to find a dr to get it fitted and I had to order it myself as NHS don’t supply it, but worth it!


Very positive mood

0 helpful

1 comments

Gynefix  
Used for 12 - 18 mo
23 years old
🇬🇧 UK
  •  4th Jan 25

Gynefix  

Got one at mortimer market in 2023 and other than a slight increase in discharge (normal discharge), which to be honest I don't think is related to the gynefix, I have had an amazing experience with the gynefix, I just wish it lasted longer than 5 years! Insertion was very smooth; uncomfortable/painful for sure but nothing terrible and not the worst pain of my life, I was able to walk home after the procedure. Had spotting / light bleeding throughout my cycle for maybe a month or two, and I remember having spotting for a few months, but honestly nothing crazy or super annoying. My period was a bit heavier for a few months after insertion but now it is back to my normal (I had light, minimal pain periods before the gynefix for context!). I love it and wish it was more available in the UK, fear that when I need it out I wont be able to get it on the NHS and I can't see myself wanting any other contraception.


Very positive mood

0 helpful

0 comments


Progestogen-only / Mini pill reviews

1398 reviews

Progestogen-only / Mini pill  
Used for 6 - 12 mo
20 years old
🇬🇧 UK
  •  1 day ago

Zelleta pill  

Started this purely to help my skin after experiencing constant hormonal breakouts, which it did clear up and meant I could eat however I wanted basically with no consequences on my skin (sugar and fatty foods). However I feel as thought the pill has really dampened my mood making me low level depressed all the time. Also experienced a decreased sex drive and lots of hair loss - but still unsure whether these are directly related.


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

After coming off a combined pill (Yasmin) that I was on for 14 years - I am now on Desogestrel, within a week I suffered a mild acne rash/breakout on chin and neck but some gel from my GP quickly sorted that. I am now 2 days late to what would have been a bleed/period and my lower back and period cramps are quite severe and prolonged - my breasts are bigger and tender to touch - hoping these symptoms begin to decrease if I get my bleed or not! Saw GP today to discuss and they’re just general side effects whilst my hormones adjust (I’m told to allow >3 months to review) - general mood has decreased a bit and I feel a bit numb emotionally but started feeling better today so fingers crossed I’m on the up!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

Switched eventually to an implant because of having to remember to bring them everywhere each day. Overall a positive experience though - a reduction in headaches, and usually say it 'flattened' my mood. Whereas before there would be some very low mood points in my cycle, this greatly reduced those. Sometimes it felt a little dull as it seemed to also reduce some of the good spikes, but this was worth it to me to not have to deal with such mood swings.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 6 - 12 mo
20 years old
🇬🇧 UK
  •  1 day ago

Zelleta pill  

Started this purely to help my skin after experiencing constant hormonal breakouts, which it did clear up and meant I could eat however I wanted basically with no consequences on my skin (sugar and fatty foods). However I feel as thought the pill has really dampened my mood making me low level depressed all the time. Also experienced a decreased sex drive and lots of hair loss - but still unsure whether these are directly related.


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
28 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

After coming off a combined pill (Yasmin) that I was on for 14 years - I am now on Desogestrel, within a week I suffered a mild acne rash/breakout on chin and neck but some gel from my GP quickly sorted that. I am now 2 days late to what would have been a bleed/period and my lower back and period cramps are quite severe and prolonged - my breasts are bigger and tender to touch - hoping these symptoms begin to decrease if I get my bleed or not! Saw GP today to discuss and they’re just general side effects whilst my hormones adjust (I’m told to allow >3 months to review) - general mood has decreased a bit and I feel a bit numb emotionally but started feeling better today so fingers crossed I’m on the up!


Somewhat negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  2 weeks ago

Desogestrel pill  

Switched eventually to an implant because of having to remember to bring them everywhere each day. Overall a positive experience though - a reduction in headaches, and usually say it 'flattened' my mood. Whereas before there would be some very low mood points in my cycle, this greatly reduced those. Sometimes it felt a little dull as it seemed to also reduce some of the good spikes, but this was worth it to me to not have to deal with such mood swings.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
22 years old
🇬🇧 UK
  •  3 weeks ago

Cerelle pill  

Got pregnant on it because I wasn’t taking it properly, since having my son and ensuring to take it regularly I have had no issues


Improved skin

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
35 years old
🇬🇧 UK
  •  3 weeks ago

Cerazette pill  

I really wanted to write about my positive experience as most people write reviews when they have a negative experience, for me the Cerazette has been really good, it improved my feeling of being in balance and lessened mood swings, it did not effect my libido, in fact in the beginning I noticed a higher libido, but most importantly I suffer from migraines with aura and since I started taking this a month ago I didn’t have an intense migraine, just one or two mild days and I normally have 2/3 days per week so in a month 8 at least. The only negative things are not too bad: I have very tender breasts which became a bit bigger but I heard this might go away after 3 months or so and I got a little bit of acne but nothing too crazy and this also usually settles after taking it consistently for a few month. All in all for me it’s truly been life changing.


Somewhat positive mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 18 mo - 3 yr
21 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

The first 3-5 months were a bit rough, having sex would cause me to get a period and sometimes was painful. I also was definitely more emotional than before. It all calms down over time, I’ve been on it for almost 3 years now and it was the best decision i get very occasionally spotting and cramps if i miss a pill or two but overall I like it


Somewhat negative mood

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 5 yr
20 years old
🇬🇧 UK
  •  1 month ago

Zelleta pill  

Went on the mini pill at 16 for 3 years. The first 9 months I bled pretty constantly (no cramps at least) then bled randomly most months. Bleeding was usually light and unpainful. My mood swings were awful and my skin broke out and got so much worse (quite discouraging after being on accutane). Didn’t notice any weight gain or other side effects. I later changed to the combined pill to try and help my skin but this caused other issues (high blood pressure, recurrent yeast infections) so last week I got the copper IUD! Would not recommend. As a 16 year old the doctor did not give me much information about my choice and the impact it would have on me. She just said “if you trust your boyfriend you don’t need to use condoms now” …


Very negative mood

1 more effect

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 1 - 3 mo
29 years old
🇬🇧 UK
  •  1 month ago

Desogestrel pill  

I was on Microgynon 30 for almost 8 years and I never had any issues! I changed 3 months ago to the progesterone only pill (Desogesterel) due to my friend getting a blood clot from microgynon, and within a month I began getting spots all over my jawline! I have now had constant spots for 2 months. I also have breakthrough bleeding which I never had on Microgynon. I will be heading back to the pharmacy to discuss my options


Worse skin

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
38 years old
🇬🇧 UK
  •  11th Jun 25

Slynd pill  

I started using slynd around 6 months ago for period control due to heavy flow and pain Initially I felt optimistic I never took the placebo green pills as I was on tricycling method I still had a period every month with ovarian pain I had a 4 week spotting episode I’ve had 3 utis which I never had in my life every month for the last 3 My sex drive dropped off the earth and there was none My mood went from frantic cycling cleaning the house and obsessing over things to emotionally crying before feeling stupid and back to normal The biggest thing for me was hair loss at least half my hair fell Out in week one I stayed commuted thinking it would get better until bald patches started to appear in month 5 that’s when I jd enough I also had graphic nightmares waking up with sweating so bad my sheets were soaked Since finished this pill I feel like I’m getting back to me with no mood swings or low mood I am 38 and maybe I needed some Oestrogen to balance it out this pill was not for me


Very negative mood

2 more effects

0 helpful

0 comments

Progestogen-only / Mini pill  
Used for 3 - 6 mo
25 years old
🇬🇧 UK
  •  6th Jun 25

Cerazette pill  

I swapped from the combined pill to Cerazette because I was having anxiety, dizziness and low libido. These have both improved since changing. The most annoying thing has been inconsistent bleeding and spotting. I won’t bleed for 3 months then will have spotting out of nowhere for 3 weeks. I have also got acne on my chin which I didn’t have before. Overall though these extra inconveniences have far outweighed the reduced anxiety, dizziness and libido issues.


Very positive mood

2 more effects

0 helpful

0 comments

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